Fig. 12.

Network properties can circumvent synaptic depression. A, A 50 msec train (100 Hz) was presented once before and twice after the tetanus (20 Hz). Post-tetanus responses to the 50 msec trains were depressed. B, Sensory response to a 50-msec-duration gap within an ongoing 20 Hz stimulus (ampullary) is shown. Responses to the gap (low-frequency component) were more than two times greater than that to the ongoing 20 Hz stimulus. C, At −0.1 nA holding current, active membrane properties further enhanced the response to the low-frequency component.