Fig. 5.

Prolonged depolarization associated with γ oscillations develops gradually with Mg²⁺ washout.A, Typical membrane potential changes of a juvenile CA1 neuron in response to paired (100 msec interstimulus interval) electrical stimuli to Schaffer collaterals in control ACSF (black line), after 30 min (dark gray line), and 60 min Mg²⁺-withdrawal (light gray line). Field (fp) and membrane potential (ic; action potentials are truncated) recordings in CA1 and CA3 strata pyramidale. B, Membrane potential changes at different time points of juvenile CA1 neurons (n = 16) in response to paired stimuli in control ACSF, after 45 and 120 min Mg²⁺ withdrawal. Time 0 msec denotes the end of the second stimulus.