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Effects of K+ channel blockers on LTP. A, Effect of HFS on IPSPs at normal (2.4 mm) [Ca2+]o(n = 8). B, Effect of charybdotoxin (open symbols; n = 9) and iberiotoxin (filled symbols;n = 5) on LTP at normal [Ca2+]o. Both toxins were present all the time. C, Effect of 1 mmCs+ on LTP at normal [Ca2+]o (n = 8). Blocker application time is indicated by the horizontal bar. D, Similar to C, but 10–50 μm 4-aminopyridine was applied (n = 7).
