Table 1.
Caspase-positive oligodendrocyte progenitors infected with AA-Akt or wt-Akt
% Caspase-positive cells | ||
---|---|---|
24 hr | 48 hr | |
Mock-infect | 8.9 ± 1.1 | 10.4 ± 1.0 |
AA-Akt | 50.1 ± 0.41-160 | 55.8 ± 1.01-160 |
wt-Akt | 10.5 ± 1.7 | 20.0 ± 1.5* |
Oligodendrocyte progenitor cells were mock-infected or infected with adenovirus expressing AA-Akt or wt-Akt. After a 24 or 48 hr infection, the virus was removed, and cells were cultured in DMEM plus 0.5% FBS for an additional 20–24 hr before caspase inhibitor stain. Caspase-positive cells were counted, and data are expressed as a percentage of total number of cells visualized by DAPI staining. Data are shown as mean ± SEM (n = 3).
F1-160: p < 0.0001;
p< 0.0060.