Table 1.

Adrenal corticosterone content inApoe^−/− and wild-type mice

Group	Adrenal weight (mg)	Corticosterone content
		ng/gland	ng/mg protein
3-Month-old mice
Wild-type (n = 5)	10.8  ± 1.3	32.6  ± 6.1	2.9  ± 0.4
Apoe−/− (n = 5)	10.3  ± 0.7	32.6  ± 5.8	3.3  ± 0.6
6-Month-old mice
Wild-type (n = 9)	10.8  ± 1.1	31.2  ± 6.1	2.9  ± 0.1
Apoe−/−(n = 9)	14.4  ± 1.6	74.0  ± 12.8*	5.9  ± 1.5

The same groups of mice were used to determine basal plasma corticosterone levels (see Fig. 1 and Results).

*p < 0.01 versus age-matched wild-type mice (Tukey–Kramer test).