Table 2.

Metabolic alterations in Apoe^−/−mice

Characteristic	6-Month-old		18-Month-old
	Wild-type	Apoe−/−	Wild-type	Apoe−/−
Body weight (gm)	33.9  ± 0.8	33.2  ± 2.0	31.2  ± 1.0	41.5  ± 3.7*
Stomach2-a	172.8  ± 20.0	229.6  ± 33.2	205.5  ± 7.1	286.3  ± 44.2*
Adipose Tissues2-a
Interscapular brown	33.6  ± 0.3	30.7  ± 1.2	38.0  ± 3.8	24.2  ± 0.4*
Mesenteric white	161.7  ± 15.6	108.4  ± 19.1	226.1  ± 14.2	197.4  ± 19.2
Epididymal white	141.8  ± 15.6	59.3  ± 4.7**	105.0  ± 10.4	74.0  ± 8.3*
Leptin (ng/ml)	6.3  ± 0.9	1.7  ± 0.5**	4.3  ± 0.8	2.6  ± 0.6*

n = 4–8 mice per group.

^F2-aValues represent mg/10 gm body weight to correct for differences in body weight.

*p < 0.05; **p < 0.01 versus wild-type (Tukey–Kramer test).