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The expression of fibronectin (A,C, E) and type IV collagen (B, D, F) in organotypic hippocampal cultures. Immunofluorescence imaging of fibronectin and type IV collagen in control slices (A,B), slices preabsorbed with fibronectin or type IV collagen (C, D), and slices pretreated with 100 nm plasmin for 6 hr (E,F). The immunofluorescence intensity is gray-coded as shown by the scale in F. Scale bar, 500 μm.
