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. 2000 Mar 1;20(5):1952–1963. doi: 10.1523/JNEUROSCI.20-05-01952.2000

Fig. 7.

Fig. 7.

5-HT innervation of the rostral pole of the nucleus accumbens. Neurotoxic effects of Meth (4 × 20 mg/kg) or PCA (2 × 10 mg/kg) on 5-HT-IR (A–C) and SERT-IR (D–F) axon terminals in the rostral pole of the NAc (interaural 11.7 mm) are shown in dark-field images. Most 5-HT axons in the rostral pole are lost after treatment. A small number of 5-HT-IR axons are spared, and these are SERT-negative (B-F). Animals were killed 14 d after drug treatment, and adjacent sections were processed for 5-HT and SERT immunocytochemistry. A, D, Saline-treated; B, E, Meth-treated; C, F, PCA-treated. Scale bar, 300 μm. ac, anterior commissure; AcC, nucleus accumbens core; AcS, nucleus accumbens shell.