Fig. 5.
Effect of selective D2, D3, or D4 antagonists on sniffing behavior in saline-treated rats (open bars) or amphetamine-treated rats (shaded bars). Sniffing Duration refers to the number of seconds spent sniffing during three 1 min intervals (see Materials and Methods). For drug name abbreviations and dosages, see the legend to Figure 3. Statistically significant (*) inhibition of amphetamine-stimulated sniffing was observed only for 10 mg/kg of L-741,626, which also significantly inhibited spontaneous sniffing.