Fig. 2.

Effect of blockade of α6β1 integrin function on Mn²⁺-stimulated neurite outgrowth on LN-1.A–C, Retinal neurons from embryonic day 16 mice were cultured on LN-1 substrata in the absence (A) or presence (B, C) of 500 μmMnCl₂. C, Cultures grown in the presence of 500 μm MnCl₂ were further treated with the function-blocking anti-α6 antibody GoH3 at 2 μg/ml. Scale bar, 50 μm.