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LTD induced by l-CCG is independent of NMDA receptor activation and is accompanied by an increase in PPF.A, Application of l-CCG (10 μm) in the presence of d-APV (50 μm) induced LTD that was not significantly different from control LTD. B, EPSPs evoked by paired stimuli in control and 60 min after the washout of l-CCG (10 μm). The control EPSP evoked by the first stimulus is scaled to that recorded 60 min after LTD induction. It is clear that there is a greater PPF after l-CCG LTD.
