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. 2000 Dec 15;20(24):9017–9024. doi: 10.1523/JNEUROSCI.20-24-09017.2000

Fig. 8.

Fig. 8.

l-CCG LTD is blocked by adenylyl cyclase and PKA inhibitors. A, Slices were incubated for at least 1 hr in 1 μm KT 5720 or 20 min in 50 μm SQ 22536 before being transferred to the recording chamber in which the same concentration of drug was maintained.l-CCG LTD normally observed in control slices was blocked in the KT 5720- or SQ 22536-treated slices. Inset shows the representative traces taken before and 60 min after the washout of l-CCG. Calibration: 10 mV, 40 msec.B, Block of l-CCG-induced initial depression by PMA. Slices were incubated for at least 1 hr in KT 5720 (1 μm) plus PMA (1 μm). Insetshows the representative traces taken before and 60 min after the washout of l-CCG. Calibration: 10 mV, 40 msec.