. 2000 Dec 15;20(24):9333–9340. doi: 10.1523/JNEUROSCI.20-24-09333.2000

Table 1.

Basal extracellular DA concentration (DA_ext) and in vivo extraction fraction (E_d) in rat Acb 3 d after a 5 d treatment with cocaine with or without the selective κ-opioid receptor agonist U-69593

Treatment	DA_ext(nm)	E_d	n
Vehicle + saline	10.9 ± 2.1	0.22 ± 0.03	12
U-69593 + saline	13.3 ± 2.1	0.11 ± 0.01^1-a	10
Vehicle + cocaine	11.4 ± 1.7	0.31 ± 0.06^1-b	12
U-69593 + cocaine	9.9 ± 2.5	0.18 ± 0.03^1-a,^1-b	13

^F1-a

U-69593 significantly decreased E_d (p < 0.05 by main effect identified by two-way ANOVA.

^F1-b

Cocaine significantly increasedE_d (p < 0.05 by main effect identified by two-way ANOVA).