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SL 327 inhibits c-fos induction by cocaine. c-fos expression was analyzed 1 hr after cocaine injection in the dorsomedial striatum (DM) and in the shell of the NA. SL 327 was injected as described Figure 4. Note the total inhibition of c-fos immunoreactivity in the DM and the strong but not total inhibition in the shell (data are representative of 4 independent mice for each group).
