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. 2000 May 1;20(9):3221–3232. doi: 10.1523/JNEUROSCI.20-09-03221.2000

Fig. 4.

Fig. 4.

BDNF increases the amplitude but does not change the kinetics of AMPA receptor-mediated mEPSCs.A, Population averages of pharmacologically isolated AMPA receptor-mediated mEPSCs from all cells in each treatment group show the increase in mEPSC amplitude induced by BDNF;n = 82, 44, and 69 for BDNF (top), control (middle), and TrkB-IgG (bottom) groups, respectively. Note that the time courses of these averaged mEPSCs are similar; data were acquired continuously under voltage clamp at 2.5 kHz and filtered at 1 kHz. B, Representative recordings of AMPA receptor-mediated mEPSCs on a compressed time base illustrate the lack of effect of BDNF treatment on mEPSC frequency;traces from neurons in BDNF (top), control (middle), and TrkB-IgG (bottom) groups are shown.