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Ethanol-induced sedation. Latency to regain righting reflex after an acute injection of 3 gm/kg ethanol at (A) 22° ambient temperature (Dbh+/−, n = 6; Dbh −/−,n = 6) and (B) 30° ambient temperature (Dbh +/−, n = 18;Dbh −/−, n = 20). DOPS (1 mg/gm) + carbidopa (0.125 mg/gm) (Dbh +/−, n= 13; Dbh −/−, n = 12) was administered 5 hr before ethanol injection. *p < 0.05; **p < 0.01; † p < 0.0001.
