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Effects of 6 nm GDNF pretreatment on WT grafts shown by TH immunocytochemistry.Arrows delineate transplants. A,B, WT grafts after GDNF pretreatment. C,D, WT grafts without GDNF pretreatment. The areas shown in higher magnification (B, D) areoutlined with corner markers in A andC. Note the increased TH cell survival and fiber outgrowth after GDNF exposure, even in wild-type grafts. Scale bar (shown in D): A, C, 100 μm; B, D, 40 μm.
