Table 1.
Size of a cortical barrel as reflected by different imaging techniques in rat and gerbil
| Rat (D1) | Gerbil (D2) | |||
|---|---|---|---|---|
| Ratio with cytochrome oxidase | Absolute size [mm2] | Absolute size [mm2] | Ratio with cytochrome oxidase | |
| 0.35 | Cytochrome oxidase | 0.092 | ||
| 5.57 | 1.95 | ORIS-605 | 0.518 | 5.63 |
| ORIS-577 | 4.211 | 45.77 | ||
| 0.57 | 0.2 | 2DG | 0.056 | 0.61 |
| fMRI 10−4 | 13.12 | 142.60 | ||
| fMRI 10−10 | 3.04 | 33.00 | ||
Data for rat D1 are from Chen-Bee et al. (1996) and for gerbil D2 from the present study. To enable a comparison, the sizes for ORIS-605 and ORIS-577 were obtained with conventional integrative analysis with scaling and clipping procedures given by Chen-Bee et al. (1996). For fMRI, a conventional level (p < 10−4, cf. Fig 1A) and a high level of significance (p< 10−10, cf. Fig 1D) are given. Note the similar ratios of ORIS-605 and of 2DG to cytochrome-oxidase in both species. Moreover, already at a level of significance ofp < 10−10 the area of the fMRI signal is somewhat smaller than that of the conventionally analyzed ORIS-577 signal.