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mGluR5 immunoreactivity in the enteric nervous system. A–D, Submucosal plexus. Clusters of mGluR5 encircle the soma of a subset of neurons. mGluR5-positive cells do not contain ChAT (B) or calcitonin gene-related peptide (C1, C2). mGluR5-immunoreactive neurons display VIP immunoreactivity (D1, D2). E,F, Myenteric plexus. A subset of mGluR5-immunoreactive neurons (E) contain calbindin (F). Scale bars, 30 μm.
