Fig. 6.
Block of associative LTD by inhibition of postsynaptic N-type Ca2+ channels via 5-HT1A receptors. A, The application of 1 μm OH-DPAT did not affect the EPSP amplitude during basal transmission. B, The EPSP amplitude during a single representative experiment is plotted against time. Voltage traces ontop are EPSPs from a single representative experiment obtained at the times indicated by the asterisks.C, The mean EPSP amplitude is plotted against time (n = 11). Note that the EPSP amplitude remains constant during application of OH-DPAT. The induction of associative LTD by APS, however, was completely blocked.