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. Author manuscript; available in PMC: 2020 Sep 10.
Published in final edited form as: Vaccine. 2019 Aug 12;37(38):5708–5716. doi: 10.1016/j.vaccine.2019.07.103

Figure 2. Addition of SA-4-1BBL improves the Th1 cellular response of the rF1-V + Alhydrogel vaccine.

Figure 2.

C57BL/6 male mice were vaccinated with rF1-V or rF1-V + Alhydrogel with increasing concentrations of SA-4-1BBL. Absolute numbers of (A) CD4+ T cells and (B) CD8+ T cells secreting IFN-γ were determined 35 d post vaccination. (C) Anti-rF1-V IgG titers of vaccinated mice were determined 28 post-vaccination. Data was analyzed by one-way ANOVA with Dunnett’s post hoc analysis compared to 0 µg of SA-4-1BBL: ****= p<0.0001; *** = p<0.001; ** = p<0.01; * = p<0.05.