Table 2.

Minimum bactericidal concentration (MBC_2h) and bactericidal NO dose (μg mL⁻¹) required to achieve 3-log reduction in bacterial viability for planktonic dental pathogens after 2 h exposure in PBS (10 mM, pH 7.4, 37 °C)^a

	Periodontal pathogens (Gram-negative)				Cariogenic bacteria (Gram-positive)
Scaffold	A. ab		P. gingivalis		A. viscosus		S. mutans
	MBC2h (mg mL−1)	NO dose (μg mL−1)	MBC2h (mg mL−1)	NO dose (μg mL−1)	MBC2h (mg mL−1)	NO dose (μg mL−1)	MBC2h (mg mL−1)	NO dose (μg mL−1)
G3-PAMAM	0.10		0.50		1		8
h-PAMAM	0.10		0.10		0.50		4
h-PAMAM/NO	0.50	20	1	39	1	39	4	156
h-PAMAM-PO-1	0.25		0.25		1		8
h-PAMAM-PO-1/NO	0.50	24	0.50	24	1	49	4	194
h-PAMAM-PO-2	0.50		2		4		>16
h-PAMAM-PO-2/NO	0.25	8	1	32	1	32	4	130
G3-PAMAM-PO	0.50		4		4		>16
G3-PAMAM-PO/NO	0.25	7	1	29	1	29	4	115

^an ≥ 3 replicates.

^bA. a is the abbreviation for A. actinomycetemcomitans.