Photomicrographs of Masson’s trichrome (A, C) or hematoxylin & eosin (B, D) stained tissues surrounding NO-releasing (A, B) and control (C, D) microdialysis probes after 14 d implantation in Sprague-Dawley rats. The photomicrographs in (A,C) stain blue for collagen fibers and those in (B, D) stain cell nuclei purple. The graph in (E) presents the glucose recovery of NO-releasing (red, triangle) and control (black, inverted triangle) microdialysis probes as a function of implantation time. Reprinted with permission from Analytical Chemistry, 2011, 83, Nichols, S. P.; Le, N. N.; Klitzman, B.; Schoenfisch, M. H. “Increased in vivo glucose recovery via nitric oxide release,” pages 1180–1184. Copyright 2011 American Chemical Society.