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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Clin Colorectal Cancer. 2017 Dec 13;17(2):85–96. doi: 10.1016/j.clcc.2017.12.004

Table 4.

Management of Ocular Conditions Associated With Anti-EGFR Therapies

Severity Dry Eye Blepharitis Eyelid Hyperemia Conjunctivitis Telangiectasias
Mild or acute Supplemental tears 4–6 times QD Lid scrubs and warm compresses for 5 min BID Fluorometholone (0.1%) 1–3 times daily (1 wk) Ophthalmic suspension of neomycin, polymyxin B sulfates, and dexamethasone (14 days) Laser therapy
Moderate/severe or chronic Tear film Eye ointment Tacrolimus (0.03%) ointment BID Ophthalmic suspension of neomycin, polymyxin B sulfates, and dexamethasone (14 days) Laser therapy
Anti-inflammatory medication Doxycycline 50 mg BID (2 wk), 50 mg QD (4 wk) Pimecrolimus cream BID

Abbreviations: BID = twice daily; EGFR = epidermal growth factor receptor; QD = once daily.