Table 2.
Psychosocial difficulties (PAHC scales) Mean (SD) |
French participants | German participants | Spanish participants | |||
T1 n=213 |
T2 n=172 |
T1 n=300 |
T2 n=220 |
T1 n=133 |
T2 n=68 |
|
Hereditary predisposition*** | 29.1 (20.2) | 22.4 (20.4) ** | 33.7 (24.1) | 23.0 (24.9) *** | 45.4 (26.6) | 35.7 (27.5) |
Familial and social issues | 15.9 (17.3) | 15.8 (16.7) | 16.6 (16.7) | 14.6 (20.4) | 11.9 (16.0) | 15.1 (20.3) |
Emotions | 30.0 (23.1) | 30.6 (24.1) | 33.8 (24.3) | 30.4 (22.8) | 29.3 (23.3) | 27.1 (24.0) |
Familial cancer | 67.7 (25.0) | 65.8 (27.5) | 51.9 (24.3) | 50.3 (25.9) | 80.0 (18.8) | 79.0 (21.4) |
Personal cancer* | 57.7 (27.0) | 54.6 (28.5) | 58.5 (28.6) | 55.0 (27.2) | 53.6 (31.8) | 48.8 (29.8) |
Children-related issues*** | 47.6 (26.7) | 41.7 (27.7) | 43.2 (26.9) | 31.4 (25.4) *** | 60.3 (25.3) | 54.8 (25.5) |
T1=assessment after the initial genetic consultation; T2=assessment 2 months after the receipt of genetic test result. PAHC score range: (0–100). Statistically significant difference between assessment times (with Bonferroni correction): *p<0.05; **p<0.01; ***p<0.001 and in bold clinically significant differences (over 10% change threshold in PAHC scale scores), overall and for each country setting.
PAHC, Psychosocial Aspects of Hereditary Cancer.