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. 2019 Sep 24;9(9):e029926. doi: 10.1136/bmjopen-2019-029926

Table 2.

Bivariate analyses of genetic-specific psychosocial difficulties mean (SD) score over assessment times, overall and for each country

Psychosocial difficulties (PAHC scales)
Mean (SD)
French participants German participants Spanish participants
T1
n=213
T2
n=172
T1
n=300
T2
n=220
T1
n=133
T2
n=68
Hereditary predisposition*** 29.1 (20.2) 22.4 (20.4) ** 33.7 (24.1) 23.0 (24.9) *** 45.4 (26.6) 35.7 (27.5)
Familial and social issues 15.9 (17.3) 15.8 (16.7) 16.6 (16.7) 14.6 (20.4) 11.9 (16.0) 15.1 (20.3)
Emotions 30.0 (23.1) 30.6 (24.1) 33.8 (24.3) 30.4 (22.8) 29.3 (23.3) 27.1 (24.0)
Familial cancer 67.7 (25.0) 65.8 (27.5) 51.9 (24.3) 50.3 (25.9) 80.0 (18.8) 79.0 (21.4)
Personal cancer* 57.7 (27.0) 54.6 (28.5) 58.5 (28.6) 55.0 (27.2) 53.6 (31.8) 48.8 (29.8)
Children-related issues*** 47.6 (26.7) 41.7 (27.7) 43.2 (26.9) 31.4 (25.4) *** 60.3 (25.3) 54.8 (25.5)

T1=assessment after the initial genetic consultation; T2=assessment 2 months after the receipt of genetic test result. PAHC score range: (0–100). Statistically significant difference between assessment times (with Bonferroni correction): *p<0.05; **p<0.01; ***p<0.001 and in bold clinically significant differences (over 10% change threshold in PAHC scale scores), overall and for each country setting.

PAHC, Psychosocial Aspects of Hereditary Cancer.