Table 1.

Summary of the PICOS elements included and excluded in the systematic review

	Inclusion criteria	Exclusion criteria
Participants	Humans Adults with at least one long-term condition Patients who can self-administer their medication Patients who are able to communicate freely and able to self-manage their medication Patients who are treated outside the hospital only	Animals Pregnant, cancer or terminally ill patients Adults with medically serious problems that are not classified as long-term conditions Patients who require assistance in taking their medication Patients who are unable to communicate or unable to self-manage their medication Inpatients or patients who are living in care homes
Intervention	Interventions of any type, intensity and frequency, which aim to investigate the effect of electronic PHRs in medication adherence, concordance, compliance or persistence	N/A
Comparators	Non-PHR	No comparison has been made with non-PHR or with usual care
Outcome	Any outcome related to the effect of electronic PHRs in medication adherence, concordance, compliance or persistence.	N/A
Study design/type	Primary studies published in the last 15 years, without any geographical restriction	Abstract-only reports without any references, commercial studies, party political statements, general discussion papers, magazine or newspaper articles, withdrawn abstracts or articles, protocols of reviews or literature reviews
Quality of the studies	Studies with moderate or high quality	Studies with low and very low quality

PHR, personal health record.