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Pre-challenge LASV-specific neutralizing antibodies. (a) Specific, dose-dependent neutralization of LASV, but not VSV, pseudovirus by LASV GPC-specific monoclonal antibody 25.1C. (b) Pre-challenge NHP serum samples collected at weeks 0 and 6 post-immunization were measured for LASV pseudovirus neutralizing activity and neutralizing EPTs calculated as described in the methods.
