Table 1.
Human rabies vaccine marketed in China.
| Cell matrix | Dose (mL) | Form | Strain | Cultivation | Purification | Potency (IU/mL) | Excipient | Preservatives | Regimen |
|---|---|---|---|---|---|---|---|---|---|
| Vero | 0.5 | liquid | PV2061 from USA ATCC | microcarrier bioreactor | 4-tandemed-columns chromatography | 4.5 | - | thiomersal | Zagreb/Essen |
| Vero | 0.5 | lyophilized | 4.5 | dextran | - | ||||
| Vero | 1.0 | lyophilized | aG strain | fixed-bed bioreactor | chromatography | 4.3 | saccharose | gentamycin | Essen |
| Vero | 0.5 | lyophilized | aG strain | fixed-bed bioreactor | chromatography | 4 | lactose/dextran/gelatin | gentamycin | Essen |
| Vero | 1.0 | lyophilized | aG strain | roller bottle | chromatography | 4 | Dextran/gelatin | Essen | |
| Vero | 1.0 | liquid | aG strain | bioreactor | chromatography | 4 | - | thiomersal | Essen |
| HDRV | 1.0 | lyophilized | PM strain | bioreactor | chromatography | 4 | maltose | kanamycin | Essen |
| PHKC | 1.0 | liquid | aG strain | roller bottle | chromatography | 4 | - | - | Essen |
| PHKC | 1.0 | liquid | aG strain | roller bottle | chromatography | 4 | - | - | Essen |
| CEF | 1.0 | lyophilized | Flury LEP strain | cell plant | gradient centrifugation | 4 | dextran | gentamycin | Zagreb/Essen |