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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Eur Neuropsychopharmacol. 2019 Jul 29;29(10):1127–1137. doi: 10.1016/j.euroneuro.2019.07.134

Figure 4: VTA DA neuron population activity was significantly lower in female rats 1–2 weeks after early adulthood stress exposure.

Figure 4:

(A) Timeline of the experiment. Adolescent female rats were submitted to a combination of FS + RS (PD65–74). Extracellular recordings of ventral tegmental area (VTA) dopamine (DA) neurons were performed between 1 and 2 week post-stress (PD81–88). (B) Population activity of DA neurons measured in cells/track, (C) Mean frequency and (D) % of spike in burst of the identified DA cells were analyzed. (B) A significant decrease in VTA DA neuron population activity was found in stressed female rats. In contrast no differences in (C) mean firing frequency or (D) burst firing were noted. No differences in (B) cells/track or (D) burst firing were noted. * p < 0.05, t-test.