Table 1:
Study sample characteristics stratified by BMI. Data presented as median (25–75 interquartile range) or sample size (%) as appropriate.
| BMI< 30 kg/m2 | BMI ≥ 30 kg/m2 | P value * | |
|---|---|---|---|
| Demographics | |||
| Age (Years) | 33.4 (25.5 – 48.6) | 38.0 (27.2 – 50.1) | 0.08 |
| Male (%) | 432 (82) | 121 (75) | 0.04 |
| Blunt mechanism (%) | 306 (58) | 82 (50) | 0.01 |
| NISS | 22.0 (11 – 34.0) | 18.0 (9.0 – 32.0) | 0.1 |
| Arrival GCS | 14.0 (6.5 – 15.0) | 15.0 (9.0 – 15.0) | < 0.01 |
| Severe TBI** | 146 (28%) | 26 (16%) | < 0.01 |
| Physiology upon hospital arrival | |||
| SBP (mmHg) | 117 (91 – 140) | 116 (90 – 140) | 0.52 |
| Base Deficit (mEq/L) | 6.8 (4 – 10) | 6.9 (3.6 – 10) | 0.99 |
| Hemoglobin (g/dL) | 13.9 (12.4 – 15.2) | 13.8 (12.6 – 15.5) | 0.50 |
| Platelet count (1,000/dL) | 250 (201 – 305) | 258 (217 – 305) | 0.13 |
| Transfusions within 24 hours postinjury | |||
| Required RBC (%) | 204 (39%) | 69 (43%) | 0.37 |
| Required plasma (%) | 199 (38) | 67 (42) | 0.41 |
| Required platelet transfusion (%) | 108 (21) | 29 (18) | 0.47 |
| Required cryoprecipitate (%) | 53 (10) | 17 (11) | 0.87 |
| Outcomes | |||
| Venous Thromboembolic Events | 17 (3.2) | 8 (5.0) | 0.31 |
| Deep Venous Thrombosis (%) | 11 (2.1) | 3 (1.9) | 0.85 |
| Pulmonary Embolus (%) | 6 (1.2%) | 5 (3.1%) | 0.08 |
| Deaths (%) | 45 (8.6) | 13 (8.1) | 0.84 |
| ICU Days | 3 (1 – 7) | 3 (1.5 – 6) | 0.98 |
| Ventilator Days | 1 (0 – 4) | 1 (0 – 3) | 0.98 |
| ICU free days | 23 (4.5 – 26) | 23 (13 – 25) | 0.84 |
| Ventilator free days | 26 (11 – 28) | 26 (18 – 28) | 0.88 |
TBI – traumatic brain injury, BMI – body mass index, NISS – New Injury Severity Score, GCS – Glasgow Coma Scale, SBP – Systolic Blood pressure, RBC – red blood cell units, ICU – intensive care unit.
*
Wilcoxon test
**
Severe TBI defined as AIS head > 2