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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Hum Immunol. 2019 Jun 27;80(9):644–660. doi: 10.1016/j.humimm.2019.05.018

Figure 1.

Figure 1

Figure 1

The graphs A and B show the differences between D’ (Figure 1A) and Wn (Figure 1B) values for the 10 two-locus haplotypes (HLA-A~HLA-C, HLA-C~HLA-B, HLA-B~HLA-DRB1, HLA-DRB1~HLA-DQA1, HLA-DRB1~HLA-DPA1, HLA-DRB1~HLA-DPB1, HLA-DQA1~HLA-DQB1, HLA-DQB1~HLA-DPA1, HLA-DQB1~HLA-DPB1 and HLA-DPA1~HLA-DPB1). The pre-fix “HLA-“ was omitted for the label of these haplotypes in the plots. The X-axis represents the genomic distance of the two loci, the Y-axis shows D’ (A) or Wn (B) values. Figures 1C-1F show heatmaps of LD measures [D’ (left panel) and Wn (right panel)] for AFA, ASI, EUR and HIS. The top-half (above the diagonal) represents the heatmap for the phased untruncated allele name haplotypes, and the bottom half represents the heatmap for the EM-estimated two-field allele name haplotypes.