Table 3.

Frequency Distribution of Top 10 HLA Alleles by Cervical hrHPV Status

	Total (n=517)		hrHPV Negative (n=392)			hrHPV Positive (n=125)
HLA Allele	Count	Frequency	Allele Count	Allele Frequency	Population Frequency	Allele Count	Allele Frequency	Population Frequency
Prevalent hrHPV
DQA1*01:02	402	0.388	286	0.364	0.602	116	0.464	0.712
DPB1*01:01	355	0.343	273	0.348	0.553	82	0.328	0.560
DQB1*06:02	284	0.274	204	0.260	0.443	80	0.320	0.520
C*04:01	282	0.272	210	0.267	0.451	72	0.288	0.472
DRB1*15:03	187	0.180	134	0.170	0.298	53	0.212	0.360
DPB1*02:01	181	0.175	133	0.169	0.301	48	0.192	0.360
B*53:01	180	0.174	133	0.169	0.306	47	0.188	0.320
DQB1*03:01	174	0.168	138	0.176	0.324	36	0.144	0.248
A*23:01	168	0.162	125	0.159	0.290	43	0.172	0.336
DQA1*05:05	146	0.141	113	0.144	0.262	33	0.132	0.208
Persistent hrHPV
	Total (n=406)		Persistent hrHPV Negative (n=355)			Persistent hrHPV Positive (n=51)
HLA Allele	Count	Frequency	Allele Count	Allele Frequency	Population Frequency	Allele Count	Allele Frequency	Population Frequency
DQA1*01:02	298	0.367	257	0.362	0.594	41	0.402	0.666
DPB1*01:01	276	0.339	234	0.3296	0.521	42	0.411	0.666
C*04:01	216	0.266	192	0.2704	0.459	24	0.235	0.333
DQB1*06:02	214	0.263	187	0.2634	0.445	27	0.264	0.431
DRB1*15:03	147	0.181	131	0.1845	0.318	16	0.156	0.254
DQB1*03:01	142	0.174	129	0.1817	0.329	13	0.127	0.254
B*53:01	140	0.172	124	0.1746	0.312	16	0.156	0.294
DPB1*02:01	137	0.168	122	0.1718	0.307	15	0.147	0.274
A*23:01	134	0.165	112	0.1577	0.290	22	0.215	0.392
DQA1*05:05	122	0.150	112	0.1577	0.281	10	0.098	0.196

hrHPV= high-risk human papillomavirus