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. Author manuscript; available in PMC: 2020 May 10.
Published in final edited form as: Blood Purif. 2019 May 10;48(3):253–261. doi: 10.1159/000500423

Table 2.

Area under the receiver-operating characteristics curve for biomarker models on day 2, 7, 14 and for the largest relative changes for predicting recovery from AKI.

Plasma biomarker Time point AUC 95%CI P*
pNGAL Day 2 0.54 0.41 to 0.69
Day 7 0.50 0.36 to 0.64
Day 14 0.55 0.37 to 0.73
Largest relative change# 0.59 0.45 to 0.74
pBNP Day 2 0.50 0.36 to 0.65
Day 7 0.58 0.45 to 0.72
Day 14 0.59 0.41 to 0.78
Largest relative change# 0.59 0.46 to 0.73
pNGAL and pBNP Day 2 0.55 0.41 to 0.68 0.89
Day 14 0.63 0.44 to 0.81 0.53
Largest relative change# 0.60 0.47 to 0.74 0.86

AUC, area under the receiver-operating characteristic curve; CI, confidence interval, pNGAL, plasma neutrophil gelatinase-associated lipocalin; pBNP, plasma B-type natriuretic peptide.

#

Largest relative change in the first 7 or 14 days as compared to day 2

*

Compared with pNGAL model on day 2, day 14 and for the largest relative change Biomarkers analysis on day 14 was performed on only 42 patients