Table 2.
Plasma biomarker | Time point | AUC | 95%CI | P* |
---|---|---|---|---|
pNGAL | Day 2 | 0.54 | 0.41 to 0.69 | |
Day 7 | 0.50 | 0.36 to 0.64 | ||
Day 14 | 0.55 | 0.37 to 0.73 | ||
Largest relative change# | 0.59 | 0.45 to 0.74 | ||
pBNP | Day 2 | 0.50 | 0.36 to 0.65 | |
Day 7 | 0.58 | 0.45 to 0.72 | ||
Day 14 | 0.59 | 0.41 to 0.78 | ||
Largest relative change# | 0.59 | 0.46 to 0.73 | ||
pNGAL and pBNP | Day 2 | 0.55 | 0.41 to 0.68 | 0.89 |
Day 14 | 0.63 | 0.44 to 0.81 | 0.53 | |
Largest relative change# | 0.60 | 0.47 to 0.74 | 0.86 |
AUC, area under the receiver-operating characteristic curve; CI, confidence interval, pNGAL, plasma neutrophil gelatinase-associated lipocalin; pBNP, plasma B-type natriuretic peptide.
Largest relative change in the first 7 or 14 days as compared to day 2
Compared with pNGAL model on day 2, day 14 and for the largest relative change Biomarkers analysis on day 14 was performed on only 42 patients