Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 1;9:14072. doi: 10.1038/s41598-019-50489-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Microarray and gene signature analysis in GBM resistant cells and survival analysis in TCGA GBM. (a) The pairwise comparison of the naïve and the resistant cell lines. (b) Heatmap using the 129 genes, fold change values are between naïve and treated. (c) Gene set enrichment analysis using the Hallmark gene sets for the up-regulated or down-regulated genes and pathways in U251 and U87 cell lines. (d) PCA signature from TMZ cell line experiment are related to survival in TCGA GBM data (p = 0.00291). (e) TCGA GBM data shows XAF1 expression is significantly related to survival of GBM patients, especially long term (p = 0.0154).