Table 2.
Comparison of averaged ion current densities measured in atrial myocytes isolated from LFD- and HFD-fed guinea pigs after 50 days.
| Current (at mV) | LFD (non-obese) (pA/pF) | n | HFD (obese) (pA/pF) | n | p |
|---|---|---|---|---|---|
| IK at +100 | 23.52 ± 1.32 | 10 | 50.7 ± 3.45* | 9 | 0.00002 |
| IKur at +100 | 12.71 ± 0.74 | 18 | 13.36 ± 0.78 | 9 | 0.56 |
| IK1 at −120 | −27.25 ± 1.67 | 20 | −26.3 ± 2.09 | 11 | 0.73 |
| ICa,L at +10 | −7.88 ± 0.57 | 16 | −2.40 ± 0.68* | 5 | 0.00010 |
Data are means ± S.E.M.
*
p < 0.05 compared to LFD non-obese controls, one-way ANOVA and Bonferroni test.