Table 1. Changes in body weights, liver weights, liver indices, and total scores gained based on the severity of liver pathology among experimental groups.
| C | FA | V | CEO10 | CEO20 | CEO100 | |
|---|---|---|---|---|---|---|
| Primary body weight (g) | 255.50±23.43 | 251.62±16.81 | 251.87±15.08 | 254.75±27.88 | 253.62±22.60 | 253.75±25.08 |
| Final body weight (g) | 294.37±12.53 | 230.75±16.49a) | 233.75±21.71a) | 239.87±17.62a) | 243.87±21.75a) | 284.75±23.10e) |
| ∆Weight (g) | 41.87±17.38 | −0.25±6.90a) | −0.12±3.97a) | 3.37±7.40a) | 10.62±3.70a) | 35.50±18.52e) |
| Liver weight (g) | 5.73±0.31 | 7.07±0.55a) | 7.05±0.38a) | 6.66±0.40c) | 6.42±0.58 | 6.01±0.65f) |
| Liver index | 1.93±0.19 | 2.83±0.37a) | 2.81±0.24a) | 2.59±0.21b) | 2.43±0.22d,g) | 2.08±0.28e) |
| Scoreh) | ||||||
| Fatty degeneration | 0 | 0 | 0 | 0 | 0 | 0 |
| Cell swelling | 0 | 3 | 3 | 3 | 2 | 2 |
| Inflammation | 0 | 4 | 4 | 3 | 3 | 1 |
| Necrosis | 0 | 4 | 4 | 4 | 2 | 1 |
| Total scores | 0 | 11 | 11 | 10 | 7 | 4 |
Values are expressed as mean±SD. C, control; FA, formaldehyde 10 mg/kg; V, FA 10 mg/kg+solvent; CEO10,20,100, FA 10 mg/kg+cinnamon essential oil 10, 20, 100 mg/kg. a)P<0.0001 when compared to control. b)P<0.001 when compared to control. c)P<0.01 when compared to control. d)P<0.05 when compared to control. e)P<0.0001 when compared to formaldehyde. f)P<0.01 when compared to formaldehyde. g)P<0.05 when compared to formaldehyde). h)Scores used to evaluate the liver pathology was as follows: score 0, no visible cell damage; score 1, focal hepatocyte damage on less than 25% of tissue; score 2, focal hepatocyte damage on 25%–50% of tissue; score 3, extensive but focal hepatocyte lesions; score 4, global hepatocyte necrosis.