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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Psychoneuroendocrinology. 2019 Jun 14;108:53–61. doi: 10.1016/j.psyneuen.2019.06.009

Fig. 4.

Fig. 4.

Responsiveness of 5αR1 knockout (KO) mice to the effects of the D1 receptor agonist SKF 82958 (SKF; 0.3 mg/kg, IP) in combination with dihydroprogesterone (DHP, 3–10 mg/kg, IP; A-B; n=8/group) and allopregnanolone (AP, 1–3 mg/kg, IP; C-D; n=12/group), on startle reflex and prepulse inhibition (PPI). Data are shown as means ± SEM. ^^^, P<0.001 in comparison with wild-type (WT) mice (Main effect of genotype); **, P<0.01, ***, P<0.001 in comparison with VEH-treated WT mice (genotype x SKF interaction). ooo, P<0.001 in comparison with KO mice treated with SKF and vehicle (VEH) (genotype x SKF x AP interaction).