Table 1. Developed and optimized nanoemulsion formulations .
Cranberry + P60 NE
(NE I) |
Curcumin + P60 NE
(NE II) |
|
Oil | Oleic Acid (10%) | Soyabean oil (13.09%) |
Surfactant | Tween 20 (20%) | Tween 20 (7.44%) |
Co-surfactant | Glycerol (3.52%) | Propylene glycol (8.25%) |
Aqueous phase | Water (66.48%) | Water (71.22%) |
Drugs | P60 (11 mg/mL) | P60 (16 mg/mL) |
Cranberry (30 mg/mL) | Curcumin (4 mg/mL) | |
Homogenise | 30 min | 20 min |
Ultrasonicate | 300 sec, 30% amplitude | 140 sec, 47% amplitude |
Abbreviations: NE, nanoemulsion; P60, polyphenon 60.