Table 2. Antimicrobial activity of developed formulations against E. coli biofilm .

Formulations		Mean % Inhibition at 0.25X MIC	Mean % Inhibition at 0.5X MIC	Mean % Inhibition at 01X MIC	Mean % Inhibition at 2X MIC
NE I	P60+Cran NE	73.97	78.37*	82.46	92.62
	Placebo	59.26	69.64	91.04	94.03
	Aqueous Solution	37.37	60.78	80.88	82.95
NE II	P60+Cur NE	56.82	76.50*	96.36*	97.28*
	Placebo	46.34	68.80	85.69	97.03
	Aqueous solution	43.36	48.51	50.13	59.62

Where MIC is the minimum inhibitory concentration; P60 is polyphenon 60; Cran is cranberry; Cur is curcumin; NE is nanoemulsion. * indicated high antibacterial activity of NEs as compared to the aqueous drug solutions. (1x concentration for P60 was 3.3 mg/mL and for Cran was 10 mg/mL and for Cur was 0.3 mg/mL).