Figure 3.

Expression of p53 in PC3 cells at 0.75µM of 5-FU and 700 µM rutin or a combination of 5-FU with rutin (0.75 µM and 700 µM respectively) for 48 h. The expression of p53 was normalized to GAPDH. Columns and bars demonstrated mean ± SD of three separate experiments. ^aP < 0.05 vs. control cells. ^bP < 0.05 vs. 5-FU treated cells.