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. 2019 May 14;13(5):705–712. doi: 10.31616/asj.2018.0257

Fig. 5.

Fig. 5.

(A–D) Immunochemical staining of Col2 (x100). Pronounced staining is found in lovastatin-treated groups (arrow). However, cells treated with TGF-β1 produce Col2 weakly. The T+L group exhibit relatively stronger Col2 staining than the T/L group. Group T: 10 ng/mL TGF-β1; group L: 5 mM lovastatin; group T+L: simultaneous treatment with 10 ng/mL TGF-β1 and 5 M lovastatin; and group T/L: sequential treatment with 10 ng/mL TGF-β1 for 72 hours then 5 M lovastatin for 11 days. Col2, collagen type II; TGF-β1, transforming growth factor-beta1.