Table 3.

Sirt1-3 inhibition for compound 11 at the thermal equilibrium (∆) and the photostationary state (PSS) after 5 minutes of 365 nm irradiation.

Entry	Sirt1 inhibitiona	Sirt2 inhibitiona	Sirt3 inhibitiona
∆	35% @ 100 µM	18.9 ± 1.38 µM	27.5 ± 3.42 µM
PSS	19% @ 100 µM	24.1 ± 1.69 µM	29.9 ± 2.11 µM

^aPercent inhibition relative to controls at the indicated concentration, n.i. = no inhibition detected.