. 2000 Feb 1;20(3):1030–1035. doi: 10.1523/JNEUROSCI.20-03-01030.2000

Table 1.

Axonal growth on Sema3A, Sema3C, and control substrates

Substrate	Average growth speed μm/hr (including collapses)	Rate of collapse (collapses/hr)	Average growth speed μm/hr (excluding collapses)
Control (n = 6)	18.6 ± 3.7	0.34 ± 0.2	19.5 ± 3.3
Sema3A (n = 21)	8.6 ± 1.2*	1.35 ± 0.2*	17.2 ± 3.1^ns
Sema3C (n = 11)	10.1 ± 2.8*	0.22 ± 0.1^ns	11.6 ± 1.9*
Downhill Sema3C (n = 9)	11.3 ± 1.2*	0.24 ± 0.1^ns	13.6 ± 2.2*
Uphill Sema3C (n = 15)	23.5 ± 2.3*	nd	nd

Growth speed and rate of growth cone collapse of cortical axons growing on a uniform membrane substrate prepared from untransfected, Sema3A-transfected, and Sema3C-transfected HEK 293 cells and on towards decreasing concentrations (downhill) of Sema3C membrane gradients. Students t test; *p < 0.05; ns, not significant; n, number of axons examined; nd, not determined.