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. 2019 Oct 1;3(4):e13610. doi: 10.2196/13610

Table 2.

Predictive accuracy to forecast major depression at 6, 12, and 18 months among primary care patients with diabetes recruited in the Diabetes–Depression Care-Management Adoption Trial study.

Predicted outcome Algorithm to predict log odds risk score of major depression AUROCa Brier score Cutoffb Sensitivity (%) Specificity (%)
6-month depression 100×exp(–4.58 + 0.55×PHQ2c + 0.13×SDSd + 0.80×PBDe + 0.80×DSSf + 0.09×DEBg) 0.80 0.07 22; 14; 8; 5 49; 70; 86; 90 88; 79; 64; 45
12-month depression 100×exp(–4.83 + 0.54×PHQ2 + 0.21×SDS + 1.26×PBD + 0.80×DSS + 0.05×DEB) 0.81 0.06 22; 14; 8; 5 56; 67; 75; 86 90; 84; 71; 56
18-month depression 100×exp(–4.53 + 0.46×PHQ2 + 0.16×SDS + 1.23×PBD + 0.62×DSS + 0.20×DEB) 0.83 0.07 22; 14; 8; 5 67; 76; 90; 91 87; 78; 64; 47

aAUROC: area under receiver operating curve.

bThe cutoff points 22, 14, 8, and 5 correspond to 100×exp(–1.5), 100×exp(–2.0), 100×exp(–2.5), and 100×exp(–3.0), respectively.

cPHQ-2: Patient Health Questionnaire - 2-item.

dSDS: Sheehan Disability Scale.

ePBD: ever had a problem with depression.

fDSS: Diabetes Symptoms Scale.

gDEB: diabetes emotional burden.