Table 2.
Predictive accuracy to forecast major depression at 6, 12, and 18 months among primary care patients with diabetes recruited in the Diabetes–Depression Care-Management Adoption Trial study.
| Predicted outcome | Algorithm to predict log odds risk score of major depression | AUROCa | Brier score | Cutoffb | Sensitivity (%) | Specificity (%) |
| 6-month depression | 100×exp(–4.58 + 0.55×PHQ2c + 0.13×SDSd + 0.80×PBDe + 0.80×DSSf + 0.09×DEBg) | 0.80 | 0.07 | 22; 14; 8; 5 | 49; 70; 86; 90 | 88; 79; 64; 45 |
| 12-month depression | 100×exp(–4.83 + 0.54×PHQ2 + 0.21×SDS + 1.26×PBD + 0.80×DSS + 0.05×DEB) | 0.81 | 0.06 | 22; 14; 8; 5 | 56; 67; 75; 86 | 90; 84; 71; 56 |
| 18-month depression | 100×exp(–4.53 + 0.46×PHQ2 + 0.16×SDS + 1.23×PBD + 0.62×DSS + 0.20×DEB) | 0.83 | 0.07 | 22; 14; 8; 5 | 67; 76; 90; 91 | 87; 78; 64; 47 |
aAUROC: area under receiver operating curve.
bThe cutoff points 22, 14, 8, and 5 correspond to 100×exp(–1.5), 100×exp(–2.0), 100×exp(–2.5), and 100×exp(–3.0), respectively.
cPHQ-2: Patient Health Questionnaire - 2-item.
dSDS: Sheehan Disability Scale.
ePBD: ever had a problem with depression.
fDSS: Diabetes Symptoms Scale.
gDEB: diabetes emotional burden.