Table 2.
Description of patient characteristics for each hospitalization in entire cohort (n=422,320), and the proportion of each grouping that died at or within seven days of discharge. Tests for mortality associated with characteristics using chi-square tests for independence or two-sample t-tests (all p<0.001 unless noted). Patient chronic conditions for each hospitalization are summarized in Supplemental Table 2.
| Patient Characteristics | Overall Sepsis Population | Death at or within 7 days of discharge |
|---|---|---|
| N= 422,320 | N= 146,729 (35%) | |
| N (% of sepsis hospitalizations) | N (% of each grouping who died within 7 days) | |
| Age- years, Mean (SD) | 79.2 (8.9) | 80.7 (9.0) |
| Gender a | ||
| Female | 217,367 (51%) | 75,950 (35%) |
| Male | 204,953 (49%) | 70,779 (35%) |
| Race | ||
| White | 341,643 (81%) | 117,875 (35%) |
| Black | 49,995 (12%) | 18,421 (37%) |
| Other | 30,682 (7%) | 10,433 (34%) |
| Gagne Score (comorbidity score), Mean (SD) | 5.2 (3.4) | 5.6 (3.4) |
| <= 2 | 100,932 (24%) | 29,526 (29%) |
| 3–5 | 139,075 (33%) | 47,562 (34%) |
| 6–8 | 106,954 (25%) | 39,636 (37%) |
| >8 | 75,359 (18%) | 30,005 (40%) |
| Admission Source | ||
| Home/Referral | 381,996 (90%) | 129,296 (34%) |
| Skilled Nursing Facility | 40,324 (10%) | 17,433 (43%) |
| Do-Not-Resuscitate Status (POA) | 88,505 (21%) | 47,870 (54%) |
| Shock Code (POA) | 211,978 (50%) | 93,436 (44%) |
| Continuous invasive mechanical ventilation (POA) | 101,748 (24%) | 57,991 (57%) |
| Hypotension (POA) | 19,340 (5%) | 6,123 (32%) |
| Transient mental disorders (POA) | 5,571 (1%) | 1,604 (29%) |
| Acute and subacute necrosis of liver or Hepatic infarction (POA) | 13,896 (3%) | 8,663 (62%) |
| Acute kidney failure (POA) | 253,359 (60%) | 90,547 (36%) |
| Shock without mention of trauma (POA) | 211,978 (50%) | 93,436 (44%) |
| Anoxic brain damage (POA) | 6,049 (1%) | 4,582 (75%) |
| Encephalopathy (POA) b | 81,309 (19%) | 28,452 (35%) |
| Thromboycytopenia (POA) | 47,157 (11%) | 17,479 (37%) |
| Defibrination syndrome (POA) | 5,359 (1%) | 3,529 (66%) |
| Coagulat defect (POA) | 6,999 (2%) | 3,986 (57%) |
| Physician visit in previous 7 days | 269,430 (64%) | 98,737 (37%) |
| Previous hospitalization (30 days) | 111,746 (26%) | 49,185 (44%) |
| Number of hospitalizations in previous year | ||
| 0 | 160,857 (38%) | 47,535 (30%) |
| 1 | 100,871 (24%) | 36,473 (36%) |
| 2–3 | 103,432 (24%) | 40,068 (39%) |
| 4+ | 57,160 (14%) | 22,653 (40%) |
| Hospital Explicit/Implicit Ratio Mean (SD) | 23.3 (8.0) | (7.9) |
a.
p=0.0055
b.
p=0.0972