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. Author manuscript; available in PMC: 2020 Jan 15.
Published in final edited form as: Toxicology. 2018 Nov 20;412:89–100. doi: 10.1016/j.tox.2018.11.005

Figure 1.

Figure 1.

The workflow to build a chemical-species phenotypic profile (CSPP) as illustrated by the 17α-ethynylestradiol_fathead minnow (EE2_FHM). A) Relevant publications were first identified from ECOTOX; B) two 17α-ethynylestradiol-induced phenotypes reported in the publication 59226 were curated manually; C) the phenotypes were annotated in Entity-Quality (EQ) syntax; D) EQ annotations were converted to their respective ontology classes in Manchester syntax; E) all annotated ontology classes for the 17α-ethynylestradiol _fathead minnow were organized into its CSPP.