Table 2.

Synthesis of isoxazole‐based spirocycles 7 using freshly‐prepared nitrile‐oxide dipole^a

^aReaction conditions: (i) 5 (1.0 equiv.), 13 (3 × 2.0 equiv.), DCE, 100 °C (MW), 3 × 30 min; (ii) 7a (1.0 equiv.), TFA (2.0 equiv.), DCM, r.t., 22 h.