Table 1.
Treatment |
p (Bonferroni's multiple-comparisons test) |
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---|---|---|---|---|---|---|---|---|---|
ABG parameter | ABG time | TC (n = 7) | Hx (n = 24) | HI (n = 21) | HI-HC (n = 8) | TC versus Hx | Hx versus HI | Hx versus HI-HC | HI versus HI-HC |
O2 content (vol %) | Pre-ABG | 7.1 ± 1.2 | 7.0 ± 1.1 | 7.0 ± 1.0 | 8.6 ± 1.2 | NS | NS | <0.05 | <0.05 |
Hx-ABG | 7.3 ± 1.2 | 4.8 ± 1.7 | 4.4 ± 1.4 | 5.6 ± 1.8 | <0.001 | NS | NS | NS | |
HI-ABG | 7.4 ± 1.2 | 4.0 ± 1.7 | 5.4 ± 2.0 | 7.1 ± 1.9 | <0.0001 | <0.01 | <0.0001 | <0.05 | |
Post-ABG | 7.2 ± 1.8 | 7.1 ± 1.0 | 7.5 ± 0.9 | 8.8 ± 1.5 | NS | NS | <0.05 | NS | |
Lactate (mm) | Pre-ABG | 1.4 ± 0.2 | 1.5 ± 0.3 | 1.5 ± 0.2 | 1.3 ± 0.3 | NS | NS | NS | NS |
Hx-ABG | 1.4 ± 0.2 | 1.5 ± 0.4 | 1.6 ± 0.2 | 1.4 ± 0.2 | NS | NS | NS | NS | |
HI-ABG | 1.3 ± 0.2 | 2.3 ± 1.2 | 3.2 ± 0.9 | 3.3 ± 0.8 | <0.05 | <0.001 | <0.01 | NS | |
Post-ABG | 1.4 ± 0.2 | 2.3 ± 1.1 | 3.8 ± 1.1 | 4.1 ± 0.9 | <0.05 | <0.0001 | <0.0001 | NS | |
Glucose (mm) | Pre-ABG | 1.4 ± 0.1 | 1.3 ± 0.1 | 1.2 ± 0.1 | 1.4 ± 0.1 | NS | NS | NS | NS |
Hx-ABG | 1.4 ± 0.1 | 1.3 ± 0.1 | 1.3 ± 0.1 | 1.5 ± 0.2 | NS | NS | NS | NS | |
HI-ABG | 1.4 ± 0.2 | 1.3 ± 0.1 | 1.6 ± 0.1 | 1.8 ± 0.2 | NS | <0.05 | <0.001 | NS | |
Post-ABG | 1.5 ± 0.2 | 1.5 ± 0.1 | 1.5 ± 0.1 | 1.8 ± 0.2 | NS | NS | NS | NS | |
Hct (%) | Pre-ABG | 29 ± 2.2 | 27 ± 2.7 | 27 ± 2.3 | 28 ± 3.6 | NS | NS | NS | NS |
Hx-ABG | 29 ± 2.2 | 27 ± 2.9 | 27 ± 2.5 | 28 ± 3.9 | NS | NS | NS | NS | |
HI-ABG | 28 ± 3.0 | 28 ± 3.1 | 29 ± 2.9 | 31 ± 3.9 | NS | NS | NS | NS | |
Post-ABG | 29 ± 2.0 | 27 ± 2.8 | 27 ± 3.3 | 29 ± 4.0 | NS | NS | NS | NS | |
Hb (g/dl) | Pre-ABG | 9.4 ± 0.7 | 8.7 ± 0.9 | 8.8 ± 0.8 | 9.2 ± 1.2 | NS | NS | NS | NS |
Hx-ABG | 9.4 ± 0.7 | 8.7 ± 1.0 | 8.8 ± 0.8 | 9.2 ± 1.3 | NS | NS | NS | NS | |
HI-ABG | 9.1 ± 1.0 | 8.9 ± 1.0 | 9.4 ± 0.9 | 9.9 ± 1.3 | NS | NS | <0.05 | NS | |
Post-ABG | 9.3 ± 0.7 | 8.8 ± 0.9 | 9.0 ± 0.8 | 9.4 ± 1.3 | NS | NS | NS | NS | |
sO2 (%) | Pre-ABG | 56 ± 8.1 | 59 ± 7.6 | 59 ± 7.4 | 70 ± 4.9 | NS | NS | NS | NS |
Hx-ABG | 57 ± 8.5 | 40 ± 13 | 37 ± 12 | 46 ± 14 | <0.01 | NS | NS | NS | |
HI-ABG | 61 ± 9.1 | 33 ± 14 | 42 ± 16 | 53 ± 14 | <0.0001 | <0.05 | <0.0001 | NS | |
Post-ABG | 57 ± 12 | 60 ± 7.4 | 62 ± 8.2 | 70 ± 8.7 | NS | NS | NS | NS | |
paO2 (mmHg) | Pre-ABG | 23 ± 2.3 | 23 ± 2.6 | 23 ± 3.0 | 25 ± 1.7 | NS | NS | NS | NS |
Hx-ABG | 23 ± 2.5 | 18 ± 3.2 | 17 ± 2.6 | 17 ± 3.6 | <0.001 | NS | NS | NS | |
HI-ABG | 24 ± 2.4 | 16 ± 4.4 | 19 ± 3.4 | 20 ± 4.4 | <0.0001 | NS | <0.05 | NS | |
Post-ABG | 23 ± 3.2 | 23 ± 3.0 | 25 ± 3.2 | 26 ± 3.1 | NS | NS | NS | NS | |
paCO2 (mmHg) | Pre-ABG | 47 ± 2.2 | 48 ± 2.3 | 48 ± 2.8 | 45 ± 2.9 | NS | NS | <0.05 | <0.05 |
Hx-ABG | 47 ± 2.5 | 45 ± 2.4 | 46 ± 2.9 | 41 ± 2.9 | NS | NS | <0.01 | <0.01 | |
HI-ABG | 45 ± 6.3 | 46 ± 3.1 | 44 ± 3.0 | 41 ± 5.3 | NS | NS | <0.001 | NS | |
Post-ABG | 48 ± 2.6 | 47 ± 2.0 | 48 ± 2.8 | 44 ± 3.3 | NS | NS | NS | <0.05 | |
pH | Pre-ABG | 7.4 ± 0.04 | 7.4 ± 0.02 | 7.4 ± 0.02 | 7.4 ± 0.02 | NS | NS | NS | NS |
Hx-ABG | 7.4 ± 0.04 | 7.4 ± 0.02 | 7.4 ± 0.01 | 7.4 ± 0.02 | <0.01 | NS | NS | NS | |
HI-ABG | 7.4 ± 0.05 | 7.4 ± 0.02 | 7.4 ± 0.03 | 7.4 ± 0.03 | NS | NS | <0.05 | <0.05 | |
Post-ABG | 7.4 ± 0.05 | 7.4 ± 0.02 | 7.4 ± 0.03 | 7.3 ± 0.03 | NS | <0.01 | <0.001 | NS |