Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
LRRK2 substrates involved in vesicle trafficking and synaptic transmission. LRRK2 phosphorylates a subset of Rab GTPases that control the endolysosomal-autophagy pathway and key molecules involved in synaptic vesicle endocytosis and recycling. Proteins that are suggested as direct substrates of LRRK2 are depicted in blue.
