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. 2019 Oct 2;14(10):e0221892. doi: 10.1371/journal.pone.0221892

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© 2019 Chong et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — Axial (left) and sagittal (right) brain maps indicateng the approximate location of 29 homotopic (left and right hemisphere) regions of interest (ROIs) on a template brain. A = anterior; P = posterior; ROIs in red indicate homotopic region-pairs with significantly strengthened functional connectivity using serial measurements of functional connectivity at two time-points; 1-month post-concussion to 5-months post-concussion. Those region-pairs that showed significant strengthening (following FDR correction for multiple comparisons per ROI) included the following: 1 = anterior insula; 3 = middle cingulate, 4 = posterior cingulate, 11 = secondary somatosensory, 21 = spinal trigeminal nucleus, 25 = precentral, 27 = pulvinar. ROIs are plotted using BrainNet Viewer (www.nitrc.org).